sparsentan will minimize the extent or outcome of modafinil by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Watch. Sparsentan (a CYP2C19 inducer) decreases exposure of CYP2C19 substrates and lessens efficacy related to these substrates. apalutamide will lessen the extent or result of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent https://modafinil13455.bloggactif.com/26628126/what-does-modafinil-mean