Hemoglobin Brockton [beta 138 (H16) Ala—-Pro] has small oxygen affinity but electrophoretic mobility and hemolysate binding are ordinary, suggesting the substitution at beta 138 will not disrupt important polar interactions, like the hydrogen bonds and salt bridges in between Asp 137 and Professional 138, that contribute on the cooperative oxygen-binding https://nicolaslecourtmansion.com